*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : NJ1925000 CHEMICAL NAME : 2-Imidazoline, 2-benzyl- CAS REGISTRY NUMBER : 59-98-3 BEILSTEIN REFERENCE NO. : 0128757 REFERENCE : 5-23-06-00488 (Beilstein Handbook Reference) LAST UPDATED : 199710 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C10-H12-N2 MOLECULAR WEIGHT : 160.24 WISWESSER LINE NOTATION : T5M CN BUTJ B1R COMPOUND DESCRIPTOR : Drug Mutagen SYNONYMS/TRADE NAMES : * Artonil * Benzazoline * Benzidazol * Benzolin * 2-Benzylimidazoline * 2-Benzyl-2-imidazoline * 2-Benzyl-4,5-imidazoline * Ciba 3259 * Divascol * Imidalin * 1H-Imidazole, 4,5-dihydro-2-(phenylmethyl)- * Kasimid * Lambril * Olitensol * Peripherine * Phenylmethylimidazoline * Prefaxil * Priscol * Priscoline * Tolazoline * Vasimid * Vasodil * Vasodilatan *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 350 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 22,514,1974 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 160 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PBPHAW Progress in Biochemical Pharmacology. (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.1- 1965- Volume(issue)/page/year: 1,542,1965 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 40 mg/kg TOXIC EFFECTS : Behavioral - tremor Behavioral - convulsions or effect on seizure threshold REFERENCE : RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 37,198,1974 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - species unspecified DOSE/DURATION : 50 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 192,141,1939 ** MUTATION DATA ** TYPE OF TEST : Cytogenetic analysis TEST SYSTEM : Rodent - hamster Lung DOSE/DURATION : 62500 ug/L REFERENCE : GMCRDC Gann Monograph on Cancer Research. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No. 11- 1971- Volume(issue)/page/year: 27,95,1981 *** STATUS IN U.S. *** EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998 *** END OF RECORD ***