*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NJ5731000
CHEMICAL NAME           : 1H-Imidazo(4,5-b)pyridine, 2-(2,4-dimethoxyphenyl)-
CAS REGISTRY NUMBER     : 77303-19-6
LAST UPDATED            : 198406
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H13-N3-O2
MOLECULAR WEIGHT        : 255.30
SYNONYMS/TRADE NAMES :
   * AR-L 57BS
   * 2-(2,4-Dimethoxyphenyl)-1H-imidazo(4,5-b)pyridine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 568 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle contraction or spasticity
   Behavioral - antipsychotic
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 31,141,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 84 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle contraction or spasticity
   Behavioral - antipsychotic
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 31,141,1981
 
                            *** END OF RECORD ***