*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NJ5749000
CHEMICAL NAME           : 1H-Imidazo(4,5-b)pyridine,
                          2-(4-methoxy-2-(2-(methylsulfinyl)ethoxy)phenyl)-
CAS REGISTRY NUMBER     : 77303-18-5
BEILSTEIN REFERENCE NO. : 0842454
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C16-H17-N3-O3-S
MOLECULAR WEIGHT        : 331.42
SYNONYMS/TRADE NAMES :
   * AR-L 100BS
   *   2-(4-Methoxy-2-(2-(methylsulfinyl)ethoxy)phenyl)-1H-imidazo(4,5-b)pyridi
     ne
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 543 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle contraction or spasticity
   Behavioral - antipsychotic
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 31,141,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 53 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle contraction or spasticity
   Behavioral - antipsychotic
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 31,141,1981
 
                            *** END OF RECORD ***