*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NJ5758500
CHEMICAL NAME           : Imidazo(1,2-a)pyridine, 2-(p-(methylsulfonyl)phenyl)-
CAS REGISTRY NUMBER     : 1222-57-7
BEILSTEIN REFERENCE NO. : 0752451
REFERENCE               : 5-23-12-00328 (Beilstein Handbook Reference)
LAST UPDATED            : 199712
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C14-H12-N2-O2-S
MOLECULAR WEIGHT        : 272.34
WISWESSER LINE NOTATION : T56 AN DNJ CR DSW1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Imidazo(1,2-a)pyridine, 2-(4-(methylsulfonyl)phenyl)-
   * 2-(4-(Methylsulfonyl)phenyl)imidazo(1,2-a)pyridine
   * Solimidin
   * Zolimidin
   * Zolimidine
   * Zoliridine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3710 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #3318880
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 950 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 33,1655,1983
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FMXXAJ French Medicament Patent Document.  (U.S. Patent and Trademark
   Office, Foreign Patents, Washington, DC 20231)  Discontinued.
   Volume(issue)/page/year: #8177M
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 765 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FMXXAJ French Medicament Patent Document.  (U.S. Patent and Trademark
   Office, Foreign Patents, Washington, DC 20231)  Discontinued.
   Volume(issue)/page/year: #8177M
 
                            *** END OF RECORD ***