*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NJ5902000
CHEMICAL NAME           : Imidazo(2,1-b)quinazoline, 1,2,3,5-tetrahydro-,
                          monohydrochloride
CAS REGISTRY NUMBER     : 33376-05-5
LAST UPDATED            : 198208
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C10-H11-N3.Cl-H
MOLECULAR WEIGHT        : 209.70
WISWESSER LINE NOTATION : T C566 BN DM GN HHT&&J &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1,2,3,5-Tetrahydroimidazo(2,1-b)quinazoline hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 900 mg/kg
TOXIC EFFECTS :
   Vascular - BP lowering not characterized in autonomic section
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 15,727,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 265 mg/kg
TOXIC EFFECTS :
   Vascular - BP lowering not characterized in autonomic section
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 15,727,1972
 
                            *** END OF RECORD ***