*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NJ8620820
CHEMICAL NAME           : 3,6-Imino-1H-2-oxa-11c-azanaphth(1,2,3-cd)azulene-5-c
                          arboxylic acid, 2a,3,4,5,6,6a,7,11b-
                          octahydro-11-methoxy-12-methyl-,
                          (2a-alpha,3-alpha,5-alpha,6-alpha,6a-alpha,11b-alpha)
                          -, (-)-
CAS REGISTRY NUMBER     : 84573-33-1
LAST UPDATED            : 199209
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C18-H22-N2-O4
MOLECULAR WEIGHT        : 330.42
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Antibiotic DC 52
   * DC 52
   * Quinocarcin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 27 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 36,463,1983
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 25 mg/L
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 37,1268,1984
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 100 mg/L
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 37,1268,1984
 
                            *** END OF RECORD ***