*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NK4800000
CHEMICAL NAME           : 1-Indancarboxylic acid, 4-(p-toluoyl)-
CAS REGISTRY NUMBER     : 56461-34-8
BEILSTEIN REFERENCE NO. : 2143608
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H16-O3
MOLECULAR WEIGHT        : 280.34
WISWESSER LINE NOTATION : L56T&J BVQ FVR D1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 4-(4-Methylbenzoyl)-1-indancarboxylic acid
   * TAI-908
   * 4-(p-Toluoyl)-1-indancarboxylic acid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 244 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - ulceration or bleeding from small intestine
   Gastrointestinal - peritonitis
   Blood - aplastic anemia
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 32,113,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 273 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - ulceration or bleeding from small intestine
   Gastrointestinal - peritonitis
   Blood - aplastic anemia
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 32,113,1982
 
                            *** END OF RECORD ***