*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : NK5335000 CHEMICAL NAME : 1,3-Indandione, 2-((p-chlorophenyl)phenylacetyl)- CAS REGISTRY NUMBER : 3691-35-8 BEILSTEIN REFERENCE NO. : 2063081 LAST UPDATED : 199612 DATA ITEMS CITED : 12 MOLECULAR FORMULA : C23-H15-Cl-O3 MOLECULAR WEIGHT : 374.83 WISWESSER LINE NOTATION : L56 BV DV CHJ CVYR&R DG COMPOUND DESCRIPTOR : Agricultural Chemical Drug Human SYNONYMS/TRADE NAMES : * Actosin C * Afnor * Baraage * CAID * Chloorfacinon * 2(2-(4-Chloor-fenyl-2-fenyl)-acetyl)-indaan-1,3-dion * Chlorfacinon * Chlorophacinone * 2-(alpha-p-Chlorophenylacetyl)indane-1,3-dione * 2-((p-Chlorophenyl)phenylacetyl)-1,3-indandione * 2(2-(4-Chlorophenyl)-2-phenylacetyl)indan-1,3-dione * 2-((4-Chlorophenyl)phenylacetyl)-1H-indene-1,3(2H)-dione * Chlorphacinon * 2(2-(4-Chlor-phenyl-2-phenyl)acetyl)indan-1,3-dion * ((4-Chlorphenyl)-1-phenyl)-acetyl-1,3-indandion * 1-(4-Chlorphenyl)-1-phenyl-acetyl-indan-1,3-dion * 2(2-(4-Cloro-fenil-2FENIL)-acetil)indan-1,3-dione * DRAT * Lepit * Liphadione * LM 91 * Microzul * Muriol * Orcomolebait * 2-(2-Phenyl-2-(4-chlorophenyl)acetyl)-1,3-indandione * Ratindan 3 * Ratomet * Redentin * Rozol * Saviac * Topitox *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - woman DOSE/DURATION : 5 mg/kg TOXIC EFFECTS : Vascular - other changes REFERENCE : JTCTDW Journal of Toxicology, Clinical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.19- 1982- Volume(issue)/page/year: 27,79,1989 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2100 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GUCHAZ Guide to the Chemicals Used in Crop Protection. (Information Canada, 171 Slater St., Ottawa, Ont., Canada) Volume(issue)/page/year: 6,112,1973 TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >3 gm/m3/1H TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year: A084,1983 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1060 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,42,1973 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 50 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GUCHAZ Guide to the Chemicals Used in Crop Protection. (Information Canada, 171 Slater St., Ottawa, Ont., Canada) Volume(issue)/page/year: 6,112,1973 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 200 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GUCHAZ Guide to the Chemicals Used in Crop Protection. (Information Canada, 171 Slater St., Ottawa, Ont., Canada) Volume(issue)/page/year: 6,112,1973 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Bird - duck DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GUCHAZ Guide to the Chemicals Used in Crop Protection. (Information Canada, 171 Slater St., Ottawa, Ont., Canada) Volume(issue)/page/year: 6,112,1973 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - species unspecified DOSE/DURATION : 7500 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GUCHAZ Guide to the Chemicals Used in Crop Protection. (Information Canada, 171 Slater St., Ottawa, Ont., Canada) Volume(issue)/page/year: 6,112,1973 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Bird - domestic DOSE/DURATION : 430 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GUCHAZ Guide to the Chemicals Used in Crop Protection. (Information Canada, 171 Slater St., Ottawa, Ont., Canada) Volume(issue)/page/year: 6,112,1973 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Bird - quail DOSE/DURATION : 720 mg/kg/90D-C TOXIC EFFECTS : Liver - changes in liver weight Blood - changes in other cell count (unspecified) Related to Chronic Data - death REFERENCE : AXVMAW Archiv fuer Experimentelle Veterinaermedizin. (S. Hirzel Verlag, Postfach 506, Leipzig DDR-7010, Ger. Dem. Rep.) V.6- 1952- Volume(issue)/page/year: 44,341,1990 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3919 No. of Facilities: 203 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 1623 (estimated) No. of Female Employees: 406 (estimated) *** END OF RECORD ***