*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NK5335000
CHEMICAL NAME           : 1,3-Indandione, 2-((p-chlorophenyl)phenylacetyl)-
CAS REGISTRY NUMBER     : 3691-35-8
BEILSTEIN REFERENCE NO. : 2063081
LAST UPDATED            : 199612
DATA ITEMS CITED        : 12
MOLECULAR FORMULA       : C23-H15-Cl-O3
MOLECULAR WEIGHT        : 374.83
WISWESSER LINE NOTATION : L56 BV DV CHJ CVYR&R DG
COMPOUND DESCRIPTOR     : Agricultural Chemical
                          Drug
                          Human
SYNONYMS/TRADE NAMES :
   * Actosin C
   * Afnor
   * Baraage
   * CAID
   * Chloorfacinon
   * 2(2-(4-Chloor-fenyl-2-fenyl)-acetyl)-indaan-1,3-dion
   * Chlorfacinon
   * Chlorophacinone
   * 2-(alpha-p-Chlorophenylacetyl)indane-1,3-dione
   * 2-((p-Chlorophenyl)phenylacetyl)-1,3-indandione
   * 2(2-(4-Chlorophenyl)-2-phenylacetyl)indan-1,3-dione
   * 2-((4-Chlorophenyl)phenylacetyl)-1H-indene-1,3(2H)-dione
   * Chlorphacinon
   * 2(2-(4-Chlor-phenyl-2-phenyl)acetyl)indan-1,3-dion
   * ((4-Chlorphenyl)-1-phenyl)-acetyl-1,3-indandion
   * 1-(4-Chlorphenyl)-1-phenyl-acetyl-indan-1,3-dion
   * 2(2-(4-Cloro-fenil-2FENIL)-acetil)indan-1,3-dione
   * DRAT
   * Lepit
   * Liphadione
   * LM 91
   * Microzul
   * Muriol
   * Orcomolebait
   * 2-(2-Phenyl-2-(4-chlorophenyl)acetyl)-1,3-indandione
   * Ratindan 3
   * Ratomet
   * Redentin
   * Rozol
   * Saviac
   * Topitox
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 5 mg/kg
TOXIC EFFECTS :
   Vascular - other changes
REFERENCE :
   JTCTDW Journal of Toxicology, Clinical Toxicology.  (Marcel Dekker, 270
   Madison Ave., New York, NY 10016)  V.19-    1982-  Volume(issue)/page/year:
   27,79,1989
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2100 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GUCHAZ Guide to the Chemicals Used in Crop Protection.  (Information Canada,
   171 Slater St., Ottawa, Ont., Canada)  Volume(issue)/page/year: 6,112,1973
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >3 gm/m3/1H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd,
   eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year:
   A084,1983
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1060 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   25,42,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GUCHAZ Guide to the Chemicals Used in Crop Protection.  (Information Canada,
   171 Slater St., Ottawa, Ont., Canada)  Volume(issue)/page/year: 6,112,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GUCHAZ Guide to the Chemicals Used in Crop Protection.  (Information Canada,
   171 Slater St., Ottawa, Ont., Canada)  Volume(issue)/page/year: 6,112,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - duck
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GUCHAZ Guide to the Chemicals Used in Crop Protection.  (Information Canada,
   171 Slater St., Ottawa, Ont., Canada)  Volume(issue)/page/year: 6,112,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 7500 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GUCHAZ Guide to the Chemicals Used in Crop Protection.  (Information Canada,
   171 Slater St., Ottawa, Ont., Canada)  Volume(issue)/page/year: 6,112,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - domestic
DOSE/DURATION           : 430 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GUCHAZ Guide to the Chemicals Used in Crop Protection.  (Information Canada,
   171 Slater St., Ottawa, Ont., Canada)  Volume(issue)/page/year: 6,112,1973
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - quail
DOSE/DURATION           : 720 mg/kg/90D-C
TOXIC EFFECTS :
   Liver - changes in liver weight
   Blood - changes in other cell count (unspecified)
   Related to Chronic Data - death
REFERENCE :
   AXVMAW Archiv fuer Experimentelle Veterinaermedizin.  (S. Hirzel Verlag,
   Postfach 506, Leipzig DDR-7010, Ger. Dem. Rep.)  V.6-    1952-
   Volume(issue)/page/year: 44,341,1990

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
   FEREAC Federal Register.  (U.S. Government Printing Office, Supt. of
   Documents, Washington, DC 20402) V.1-    1936-  Volume(issue)/page/year:
   54,7740,1989

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X3919
       No. of Facilities: 203 (estimated)
       No. of Industries: 1
       No. of Occupations: 2
       No. of Employees: 1623 (estimated)
       No. of Female Employees: 406 (estimated)

 
                            *** END OF RECORD ***