*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NK6300000
CHEMICAL NAME           : 1,3-Indandione, 2-pivaloyl-
CAS REGISTRY NUMBER     : 83-26-1
BEILSTEIN REFERENCE NO. : 2051258
REFERENCE               : 4-07-00-02791 (Beilstein Handbook Reference)
LAST UPDATED            : 199801
DATA ITEMS CITED        : 27
MOLECULAR FORMULA       : C14-H14-O3
MOLECULAR WEIGHT        : 230.28
WISWESSER LINE NOTATION : L56 BV DV CHJ CVX1&1&1
COMPOUND DESCRIPTOR     : Agricultural Chemical
SYNONYMS/TRADE NAMES :
   * Chemrat
   * Contrax-P
   * 2-(2,2-Dimethyl-1-oxopropyl)-1H-indene-1,3(2H)-dione
   * 1,3-Indandione, 2-pivalyl-
   * Latka 333
   * Paracakes
   * Para-Pac
   * Pindon
   * Pindone
   * Pivacin
   * Pival
   * Pivaldion
   * Pivaldione
   * 2-Pivaloyl-indaan-1,3-dion
   * 2-Pivaloyl-indan-1,3-dion
   * 2-Pivaloyl-1,3-indandione
   * 2-Pivaloylindane-1,3-dione
   * 2-Pivalyl-1,3-indandione
   * Pivalyl valone
   * Tri-ban
   * 2-Trimethylacetyl-1,3-indandione
   * 2-(Trimetil-acetil)-indan-1,3-dione
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 280 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   2,88,1960
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YKYUA6 Yakkyoku.  Pharmacy.  (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo,
   Japan)  V.1-    1950-  Volume(issue)/page/year: 31,1385,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GUCHAZ Guide to the Chemicals Used in Crop Protection.  (Information Canada,
   171 Slater St., Ottawa, Ont., Canada)  Volume(issue)/page/year: 6,415,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 75 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GYAV "Pflanzenschutz-und Schaedlingsbekaempfungsmittel: Abriss einer
   Toxikologie und Therapie von Vergiftungen," 2nd ed., Klimmer, O.R.,
   Hattingen, Fed. Rep. Ger., Hundt-Verlag, 1971  Volume(issue)/page/year:
   -,118,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85DPAN "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel,"
   Perkow, W., Berlin, Verlag Paul Parey, 1971-1976  Volume(issue)/page/year:
   -,-,1971/1976
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - domestic
DOSE/DURATION           : 75 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AWLRAO Australian Wildlife Research.  (Commonwealth Scientific and
   Industrial Research Organization, 314 Albert St., E. Melbourne, Vic. 3002,
   Australia)  V.1-  1974-  Volume(issue)/page/year: 5,135,1978
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 350 ug/kg/7D-C
TOXIC EFFECTS :
   Blood - hemorrhage
   Related to Chronic Data - death
REFERENCE :
   AWLRAO Australian Wildlife Research.  (Commonwealth Scientific and
   Industrial Research Organization, 314 Albert St., E. Melbourne, Vic. 3002,
   Australia)  V.1-  1974-  Volume(issue)/page/year: 5,135,1978
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - domestic
DOSE/DURATION           : 85400 ug/kg/7D-C
TOXIC EFFECTS :
   Behavioral - food intake (animal)
   Blood - change in clotting factors
REFERENCE :
   AWLRAO Australian Wildlife Research.  (Commonwealth Scientific and
   Industrial Research Organization, 314 Albert St., E. Melbourne, Vic. 3002,
   Australia)  V.1-  1974-  Volume(issue)/page/year: 5,135,1978

                              *** REVIEWS ***
 
   ACGIH TLV-TWA 0.1 mg/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
   FEREAC Federal Register.  (U.S. Government Printing Office, Supt. of
   Documents, Washington, DC 20402) V.1-    1936-  Volume(issue)/page/year:
   54,7740,1989

   MSHA STANDARD-air:TWA 0.1 mg/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   3,213,1971

   OSHA PEL (Gen Indu):8H TWA 0.1 mg/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1910.1000,1994

   OSHA PEL (Construc):8H TWA 0.1 mg/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1926.55,1994

   OSHA PEL (Shipyard):8H TWA 0.1 mg/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1915.1000,1993

   OSHA PEL (Fed Cont):8H TWA 0.1 mg/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   41,50-204.50,1994

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-AUSTRALIA:TWA 0.1 mg/m3 JAN 1993
   
   OEL-BELGIUM:TWA 0.1 mg/m3 JAN 1993
   
   OEL-DENMARK:TWA 0.01 mg/m3 JAN 1993
   
   OEL-DENMARK:TWA 0.1 mg/m3 JAN 1993
   
   OEL-FRANCE:TWA 0.1 mg/m3 JAN 1993
   
   OEL-THE NETHERLANDS:TWA 0.1 mg/m3 JAN 1993
   
   OEL-SWITZERLAND:TWA 0.1 mg/m3 JAN 1993
   
   OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
   
   OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
   NIOSH REL TO PINDONE-air:10H TWA 0.1 mg/m3
REFERENCE :
   NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
   Health, Education, and Welfare, Reports and Memoranda.
   Volume(issue)/page/year: DHHS #92-100,1992

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 60110
       No. of Facilities: 769 (estimated)
       No. of Industries: 7
       No. of Occupations: 9
       No. of Employees: 6855 (estimated)
       No. of Female Employees: 1432 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***