*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NL3521875
CHEMICAL NAME           : 1H-Indole-3-acetic acid,
                          1-(4-chlorobenzoyl)-5-methoxy-2-methyl-,
                          1,3-dihydro-3-oxo-1- isobenzofuranyl ester
CAS REGISTRY NUMBER     : 67489-39-8
LAST UPDATED            : 199703
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C27-H20-Cl-N-O6
MOLECULAR WEIGHT        : 489.93
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-(p-Chlorbenzoyl)-5-methoxy-2-methylindol-3-acet-3-oxy-1-isobenzofuranyl 
    ester
   * 1,3-Dihydro-3-oxo-1-isobenzofuranyl  
   1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate
   * Talmetacin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 20089 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GWXXBX German Offenlegungsschrift Patent Document.  (U.S. Patent and
   Trademark Office, Foreign Patents, Washington, DC 20231)
   Volume(issue)/page/year: #3005827
 
                            *** END OF RECORD ***