*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NL3668500
CHEMICAL NAME           : Indole-3-acetohydroxamic acid,
                          1-(p-chlorobenzoyl)-5-methoxy-2-methyl-
CAS REGISTRY NUMBER     : 27035-30-9
BEILSTEIN REFERENCE NO. : 0497721
REFERENCE               : 5-22-05-00243 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C19-H17-Cl-N2-O4
MOLECULAR WEIGHT        : 372.83
WISWESSER LINE NOTATION : T56 BNJ BVR DG& C1 D1VMQ GO1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * ABC 8/3
   * Acido 1-(p-clorobenzoil)-5-metossi-2-metil-3-indolilacetoidrossamico
   * Acido indoxamico
   * 1-(4-Chlorobenzoyl)-N-hydroxy-5-methoxy-2-methyl-1H-indole-3-acetamide
   * 1-(p-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetohydroxamic acid
   * 1-(p-Chlorobenzoyl)-5-methoxy-2-methyl-3-indolylacetohydroxamic acid
   * Flogar
   * 1H-Indole-3-acetamide, 1-(4-chlorobenzoyl)-N-hydroxy-5-methoxy-2-methyl-
   * Indoxamic acid
   * Oxametacin
   * Oxamethacin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 78 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   114,319,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 40 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   114,319,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 92 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   114,319,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 32 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   114,319,1975
 
                            *** END OF RECORD ***