*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NL4056000
CHEMICAL NAME           : Indole, 3-(1-aminoethyl)-, hydrochloride
LAST UPDATED            : 198503
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C10-H12-N2.Cl-H
MOLECULAR WEIGHT        : 196.70
SYNONYMS/TRADE NAMES :
   * 3-(1-Aminoethyl)indole hydrochloride
   * alpha-Indolaethylamin salzsaeure
   * alpha-Indoleethylamine hydrochloride
   * Lutamin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - muscle weakness
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   TKIZAM Tokyo Igaku Zasshi.  Tokyo Journal of Medical Sciences.  (Tokyo,
   Japan)  V.59-76, 1951-68.  Volume(issue)/page/year: 36,117,1922
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 700 mg/kg
TOXIC EFFECTS :
   Behavioral - muscle weakness
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   TKIZAM Tokyo Igaku Zasshi.  Tokyo Journal of Medical Sciences.  (Tokyo,
   Japan)  V.59-76, 1951-68.  Volume(issue)/page/year: 36,117,1922
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Amphibian - frog
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Behavioral - muscle weakness
REFERENCE :
   TKIZAM Tokyo Igaku Zasshi.  Tokyo Journal of Medical Sciences.  (Tokyo,
   Japan)  V.59-76, 1951-68.  Volume(issue)/page/year: 36,117,1922
 
                            *** END OF RECORD ***