*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : NL4375000 CHEMICAL NAME : Indole, 3-(2-aminoethyl)-, monohydrochloride CAS REGISTRY NUMBER : 343-94-2 LAST UPDATED : 199701 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C10-H12-N2.Cl-H MOLECULAR WEIGHT : 196.70 WISWESSER LINE NOTATION : T56 BMJ D2Z &GH COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * 3-(2-Aminoethyl)indole hydrochloride * beta-Indolaethylamin-chlorhydrat * beta-3-Indolylethylamine hydrochloride * Indole-3-ethylamine hydrochloride * beta-Indole-ethylamine hydrochloride * Tryptamine hydrochloride *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1300 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPMRAB Japanese Journal of Medical Sciences, Part 4: Pharmacology. (Tokyo, Japan) V.1-16, 1926-43. For publisher information, see JJPAAZ. Volume(issue)/page/year: 2,77,1927 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 197 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 94,1620,1974 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 504 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 33,180,1970 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 109 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 23,43,1964 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPMRAB Japanese Journal of Medical Sciences, Part 4: Pharmacology. (Tokyo, Japan) V.1-16, 1926-43. For publisher information, see JJPAAZ. Volume(issue)/page/year: 2,77,1927 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4652 No. of Facilities: 10 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 34 (estimated) No. of Female Employees: 3 (estimated) *** STATUS IN U.S. *** EPA TSCA Section 8(b) CHEMICAL INVENTORY *** END OF RECORD ***