*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NL4375000
CHEMICAL NAME           : Indole, 3-(2-aminoethyl)-, monohydrochloride
CAS REGISTRY NUMBER     : 343-94-2
LAST UPDATED            : 199701
DATA ITEMS CITED        : 7
MOLECULAR FORMULA       : C10-H12-N2.Cl-H
MOLECULAR WEIGHT        : 196.70
WISWESSER LINE NOTATION : T56 BMJ D2Z &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 3-(2-Aminoethyl)indole hydrochloride
   * beta-Indolaethylamin-chlorhydrat
   * beta-3-Indolylethylamine hydrochloride
   * Indole-3-ethylamine hydrochloride
   * beta-Indole-ethylamine hydrochloride
   * Tryptamine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPMRAB Japanese Journal of Medical Sciences, Part 4:  Pharmacology. (Tokyo,
   Japan)  V.1-16, 1926-43. For publisher information, see JJPAAZ.
   Volume(issue)/page/year: 2,77,1927
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 197 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YKKZAJ Yakugaku Zasshi.  Journal of Pharmacy.  (Nippon Yakugakkai, 2-12-15
   Shibuya, Shibuya-ku, Tokyo 150, Japan)  No.1-    1881-
   Volume(issue)/page/year: 94,1620,1974
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 504 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   RPTOAN Russian Pharmacology and Toxicology (English Translation).
   Translation of FATOAO.  (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey,
   UK)  V.30-    1967-  Volume(issue)/page/year: 33,180,1970
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 109 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 23,43,1964
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPMRAB Japanese Journal of Medical Sciences, Part 4:  Pharmacology. (Tokyo,
   Japan)  V.1-16, 1926-43. For publisher information, see JJPAAZ.
   Volume(issue)/page/year: 2,77,1927

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X4652
       No. of Facilities: 10 (estimated)
       No. of Industries: 2
       No. of Occupations: 2
       No. of Employees: 34 (estimated)
       No. of Female Employees: 3 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***