*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NL5300000
CHEMICAL NAME           : Indole, 3-((tert-butylamino)acetyl)-, hydrochloride,
                          hydrate
CAS REGISTRY NUMBER     : 78907-16-1
LAST UPDATED            : 198609
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C14-H18-N2-O.Cl-H.H2-O
MOLECULAR WEIGHT        : 284.82
WISWESSER LINE NOTATION : T56 BMJ DV1MX1&1&1 &GH &QH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 3-(tert-Butylamino)acetylindole hydrochloride hydrate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 410 mg/kg
TOXIC EFFECTS :
   Behavioral - wakefulness
   Nutritional and Gross Metabolic - body temperature increase
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 15,412,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 275 ug/kg
TOXIC EFFECTS :
   Behavioral - wakefulness
   Nutritional and Gross Metabolic - body temperature increase
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 15,412,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 90 mg/kg
TOXIC EFFECTS :
   Behavioral - wakefulness
   Nutritional and Gross Metabolic - body temperature increase
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 15,412,1981
 
                            *** END OF RECORD ***