*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NL7170000
CHEMICAL NAME           : Indole,
                          5,6-dimethoxy-2-methyl-3-(2-(4-phenyl-1-piperazinyl)e
                          thyl)-
CAS REGISTRY NUMBER     : 153-87-7
BEILSTEIN REFERENCE NO. : 0899339
REFERENCE               : 5-23-03-00112 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C23-H29-N3-O2
MOLECULAR WEIGHT        : 379.55
WISWESSER LINE NOTATION : T56 BMJ C1 GO1 HO1 D2- AT6N DNTJ DR
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Equipertine
   * Forit
   * 1H-Indole, 5,6-dimethoxy-2-methyl-3-(2-(4-phenyl-1-piperazinyl)ethyl)-
   * Integrin
   * Opertil
   * Oxypertin
   * Oxypertine
   * WIN 18501-2
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,154,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,154,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 154 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - rigidity (including catalepsy)
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 26,186,1966
 
                            *** END OF RECORD ***