*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NL9750000
CHEMICAL NAME           : Indole, 5-methoxy-3-(2-morpholinoethyl)-, oxalate
LAST UPDATED            : 198505
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C15-H20-N2-O2.C2-H2-O4
MOLECULAR WEIGHT        : 350.41
WISWESSER LINE NOTATION : T56 BMJ D2- AT6N DOTJ& GO1 &QVVQ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 5-Methoxy-3-(beta-morpholinoethyl)indole oxalate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Behavioral - changes in motor activity (specific assay)
   Behavioral - ataxia
REFERENCE :
   DIPHAH Dissertationes Pharmaceuticae.  (Warsaw, Poland)  V.1-17, 1949-65.
   For publisher information, see PJPPAA.  Volume(issue)/page/year: 14,247,1962
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 42 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Behavioral - changes in motor activity (specific assay)
   Behavioral - ataxia
REFERENCE :
   DIPHAH Dissertationes Pharmaceuticae.  (Warsaw, Poland)  V.1-17, 1949-65.
   For publisher information, see PJPPAA.  Volume(issue)/page/year: 14,247,1962
 
                            *** END OF RECORD ***