*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NM1925000
CHEMICAL NAME           : 5,6-Indolinedione, 3-hydroxy-1-methyl-
CAS REGISTRY NUMBER     : 54-06-8
LAST UPDATED            : 199206
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C9-H9-N-O3
MOLECULAR WEIGHT        : 179.19
WISWESSER LINE NOTATION : T56 BN GVVT&J B1 DQ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Adraxone
   * Adrenochrome
   * 2,3-Dihydro-3-hydroxy-1-methyl-1H-indole-5,6-dione
   * 3-Hydroxy-1-methyl-5,6-indolinedione
   * 1H-Indole-5,6-dione, 2,3-dihydro-3-hydroxy-1-methyl-
   * USAF uctl-7
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 106,90,1956
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD277-689
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 128 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 106,90,1956
 
                            *** END OF RECORD ***