*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AU7400000
CHEMICAL NAME           : Adenosine, 4'-C-fluoro-, 5'-sulfamate
CAS REGISTRY NUMBER     : 24751-69-7
LAST UPDATED            : 199504
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C10-H13-F-N6-O6-S
MOLECULAR WEIGHT        : 364.35
WISWESSER LINE NOTATION : T56 BN DN FN HNJ IZ D- ET5OTJ BF B1OSZW CQ DQ
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Antibiotic T-3018
   * 4'-C-Fluoroadenosine 5'-sulfamate
   * 4'-Fluoro-5'-O-sulfamoyladenosine
   * 9-(4-Fluoro-5-O-sulfamoylpentofuranosyl)adenine
   * Nucleocidin
   * T-3018
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 5,297,1981
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 ug/kg
TOXIC EFFECTS :
   Blood - other changes
REFERENCE :
   ABANAE Antibiotics Annual.  (New York, NY)  1953-60.  For publisher
   information, see AMACCQ.  Volume(issue)/page/year: 4,716,1956/1957
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Mammal - cattle
DOSE/DURATION           : 50 ug/kg
TOXIC EFFECTS :
   Blood - other changes
REFERENCE :
   ABANAE Antibiotics Annual.  (New York, NY)  1953-60.  For publisher
   information, see AMACCQ.  Volume(issue)/page/year: 4,716,1956/1957
 
                            *** END OF RECORD ***