*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AU7410000
CHEMICAL NAME           : Adenosine, 5'-S-methyl-5'-thio-
CAS REGISTRY NUMBER     : 2457-80-9
BEILSTEIN REFERENCE NO. : 0042420
REFERENCE               : 4-26-00-03675 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C11-H15-N5-O3-S
MOLECULAR WEIGHT        : 297.37
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * 5'-(Methylthio)adenosine
   * 5'-S-Methylthioadenosine
   * Vitamin L(sub 2)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JKXXAF Japanese Kokai Tokyo Koho Patents.  (U.S. Patent and Trademark
   Office, Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year:
   #92-46124
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 100 umol/L
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 8,653,1987
 
                            *** END OF RECORD ***