*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AX7715000
CHEMICAL NAME           : Ajmalan-17,21-diol, (17S,21-alpha)-,
                          (R-(R*,R*))-2,3-dihydroxybutanedioate (1:1) (salt)
LAST UPDATED            : 199712
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H26-N2-O2.C4-H6-O6
MOLECULAR WEIGHT        : 476.58
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (17S,21-alpha)-Ajmalan-17,21-diol (R-(R*,R*))-2,3-dihydroxybutanedioate  
   (1:1) (salt)
   * Sandwicine hydrogen tartrate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 729 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4558052
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 155 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4558052
 
                            *** END OF RECORD ***