*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AX7730000
CHEMICAL NAME           : Ajmalan-17,21-diol, 4-oxide, (17R,21-alpha)-
CAS REGISTRY NUMBER     : 68622-80-0
LAST UPDATED            : 199603
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H26-N2-O3
MOLECULAR WEIGHT        : 342.48
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Ajmaline N-oxide
   * N-Oxyajmaline
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 476 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4148898
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >3400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4148898
 
                            *** END OF RECORD ***