*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AX8153000
CHEMICAL NAME           : Ajmaline, succinate, methyl ester, hydrochloride
CAS REGISTRY NUMBER     : 107965-09-3
LAST UPDATED            : 198806
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C25-H32-N2-O5.Cl-H
MOLECULAR WEIGHT        : 477.05
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Monocarbometossipropionilajmalina cloridrato
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 35 mg/kg
TOXIC EFFECTS :
   Cardiac - change in rate
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 19,865,1964
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 27 mg/kg
TOXIC EFFECTS :
   Cardiac - change in rate
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 19,865,1964
 
                            *** END OF RECORD ***