*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AY2961500
CHEMICAL NAME           : D-Alaninamide,
                          N-acetyl-4-chloro-D-phenylalanyl-4-chloro-D-phenylala
                          nyl-D-tryptophyl-L-se ryl-
                          L-tyrosyl-D-phenylalanyl-L-leucyl-L-arginyl-L-prolyl-
CAS REGISTRY NUMBER     : 78493-58-0
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C72-H89-Cl2-N15-O13
MOLECULAR WEIGHT        : 1443.66
COMPOUND DESCRIPTOR     : Reproductive Effector
                          Hormone
SYNONYMS/TRADE NAMES :
   * Des-Gly(sup 10)-GNRH D-alanylamide
   * Gonadotropin-releasing hormone, des-gly(sup 10)-, D-alaninamide
   * ORG 30093
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 8 mg/kg
SEX/DURATION            : male 4 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
   BIREBV Biology of Reproduction.  (Soc. for the Study of Reproduction, 309 W.
   Clark St., Champaign, IL 61820)  V.1-    1969-  Volume(issue)/page/year:
   32,721,1985
 
                            *** END OF RECORD ***