*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AY2961550
CHEMICAL NAME           : D-Alaninamide,
                          N-acetyl-3-(1-naphthalenyl)-D-alanyl-4-chloro-D-pheny
                          lalanyl-D-phenylalany l-L-
                          seryl-L-tyrosyl-D-arginyl-L-phenylalanyl-L-arginyl-L-
                          prolyl-
CAS REGISTRY NUMBER     : 127545-69-1
OTHER CAS REGISTRY NOS. : 115950-83-9
LAST UPDATED            : 199706
DATA ITEMS CITED        : 1
COMPOUND DESCRIPTOR     : Reproductive Effector
                          Hormone
SYNONYMS/TRADE NAMES :
   * (N-Acetyl-D-beta-Nall-D-pCl-Phe2-D-Phe3-D-Arg6-Phe7-Arg8-D-Ala10)NH2 GnRH
   * BIM 21009
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Primate - monkey
DOSE                    : 570 ug/kg
SEX/DURATION            : female 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - menstrual cycle changes or disorders
   Reproductive - Maternal Effects - other effects
REFERENCE :
   JRPFA4 Journal of Reproduction and Fertility.  (Biochemical Soc. Book Depot,
   POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK)  V.1-    1960-
   Volume(issue)/page/year: 82,743,1988
 
                            *** END OF RECORD ***