*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : AU7480500 CHEMICAL NAME : 5'-Adenylic acid CAS REGISTRY NUMBER : 61-19-8 BEILSTEIN REFERENCE NO. : 0054612 REFERENCE : 4-26-00-03615 (Beilstein Handbook Reference) LAST UPDATED : 199701 DATA ITEMS CITED : 9 MOLECULAR FORMULA : C10-H14-N5-O7-P MOLECULAR WEIGHT : 347.26 WISWESSER LINE NOTATION : T56 BN DN FN HNJ IZ D- BT5OTJ CQ DQ E1OPQQO COMPOUND DESCRIPTOR : Mutagen Reproductive Effector SYNONYMS/TRADE NAMES : * Adenosine 5'-monophosphate * Adenosine-5-monophosphoric acid * Adenosine-5'-monophosphoric acid * Adenosine phosphate * Adenosine 5'-phosphate * Adenosine 5'-phosphoric acid * Adenovite * Adenyl * Adenylic acid * tert-Adenylic acid * AMP * A5MP * 5-Amp * 5'-Amp * AMP (nucleotide) * Cardiomone * Ergadenylic acid * Lycedan * Muscle adenylic acid * MY-B-Den * Myoston * NSC-20264 * Phosaden * Phosphaden * Phosphentaside *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 4 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 20,160,1986 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE : 2800 mg/kg SEX/DURATION : female 7-13 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) REFERENCE : OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 4,625,1970 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE : 2800 mg/kg SEX/DURATION : female 7-13 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) REFERENCE : OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 4,625,1970 ** MUTATION DATA ** TYPE OF TEST : Mutation test systems - not otherwise specified TEST SYSTEM : Human Cells - not otherwise specified DOSE/DURATION : 100 umol/L REFERENCE : JIDEAE Journal of Investigative Dermatology. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1938- Volume(issue)/page/year: 65,52,1975 TYPE OF TEST : DNA inhibition TEST SYSTEM : Rodent - rat Liver DOSE/DURATION : 10 mmol/L REFERENCE : CYTBAI Cytobios. (Faculty Press, 88 Regent St., Cambridge, UK) V.1- 1969- Volume(issue)/page/year: 4,121,1971 TYPE OF TEST : Mutation test systems - not otherwise specified TEST SYSTEM : Rodent - rat Liver DOSE/DURATION : 10 mmol/L REFERENCE : CYTBAI Cytobios. (Faculty Press, 88 Regent St., Cambridge, UK) V.1- 1969- Volume(issue)/page/year: 4,121,1971 TYPE OF TEST : Mutation test systems - not otherwise specified TEST SYSTEM : Rodent - mouse Cells - not otherwise specified DOSE/DURATION : 50 umol/L REFERENCE : JIDEAE Journal of Investigative Dermatology. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1938- Volume(issue)/page/year: 66,313,1976 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3805 No. of Facilities: 973 (estimated) No. of Industries: 2 No. of Occupations: 9 No. of Employees: 12179 (estimated) No. of Female Employees: 8315 (estimated) *** STATUS IN U.S. *** EPA TSCA Section 8(b) CHEMICAL INVENTORY *** END OF RECORD ***