*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : AY3850000 CHEMICAL NAME : Alanine, 3-(p-(bis(2-chloroethyl)amino)phenyl)-N-formyl-, L- CAS REGISTRY NUMBER : 35849-41-3 OTHER CAS REGISTRY NOS. : 32526-17-3 LAST UPDATED : 199706 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C14-H18-Cl2-N2-O3 MOLECULAR WEIGHT : 333.24 WISWESSER LINE NOTATION : QVYMVH1R DN2G2G -L COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * Alanine, 3-(p-(bis(2-chloroethyl)amino)phenyl)-N-formyl-, (-)- * L-3-(p-(Bis(2-chloroethyl)amino)phenyl)-N-formylalanine * CB 3208 * N-Formylmelphalan * N-Formyl-L-p-sarcolysin *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 700 mg/kg TOXIC EFFECTS : Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain REFERENCE : AICCA6 Acta Unio Internationalis Contra Cancrum. (Louvain, Belgium) V.1-20, 1936-64. For publisher information, see IJCNAW. Volume(issue)/page/year: 20,144,1964 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 80 mg/kg TOXIC EFFECTS : Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain REFERENCE : AICCA6 Acta Unio Internationalis Contra Cancrum. (Louvain, Belgium) V.1-20, 1936-64. For publisher information, see IJCNAW. Volume(issue)/page/year: 20,144,1964 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 730 mg/kg TOXIC EFFECTS : Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain REFERENCE : AICCA6 Acta Unio Internationalis Contra Cancrum. (Louvain, Belgium) V.1-20, 1936-64. For publisher information, see IJCNAW. Volume(issue)/page/year: 20,144,1964 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 150 mg/kg TOXIC EFFECTS : Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain REFERENCE : AICCA6 Acta Unio Internationalis Contra Cancrum. (Louvain, Belgium) V.1-20, 1936-64. For publisher information, see IJCNAW. Volume(issue)/page/year: 20,144,1964 *** END OF RECORD ***