*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AY4200000
CHEMICAL NAME           : Alanine, N,N-bis(2-chloroethyl)-, hydrochloride, DL-
CAS REGISTRY NUMBER     : 3374-04-7
LAST UPDATED            : 199203
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C7-H13-Cl2-N-O2.Cl-H
MOLECULAR WEIGHT        : 250.57
WISWESSER LINE NOTATION : QVY1&N2G2G &GH -R
SYNONYMS/TRADE NAMES :
   * Alanine mustard
   * N,N-Bis(beta-chloroethyl)-D,L-alanine hydrochloride
   * NSC 17663
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intracerebral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 225 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 18,760,1966
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 1250 ug/kg
TOXIC EFFECTS :
   Gastrointestinal - other changes
   Blood - leukopenia
   Blood - other changes
REFERENCE :
   CCSUBJ Cancer Chemotherapy Reports, Part 2.  (Washington, DC)  V.1-5,
   1964-75.  For publisher information, see CTRRDO.  Volume(issue)/page/year:
   2,201,1965
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Primate - monkey
DOSE/DURATION           : 1250 ug/kg
TOXIC EFFECTS :
   Blood - leukopenia
   Blood - other changes
REFERENCE :
   CCSUBJ Cancer Chemotherapy Reports, Part 2.  (Washington, DC)  V.1-5,
   1964-75.  For publisher information, see CTRRDO.  Volume(issue)/page/year:
   2,201,1965
 
                            *** END OF RECORD ***