*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AU7482700
CHEMICAL NAME           : 5'-Adenylic acid, polymers, complex with 5'-uridylic
                          acid polymers (1:1)
CAS REGISTRY NUMBER     : 24936-38-7
LAST UPDATED            : 199706
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : (C10-H14-N5-O7-P)n.(C9-H13-N2-O9-P)n
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * 5'-Adenylic acid, homopolymer, complex with 5'-uridylic acid homopolymer  
   (1:1)
   * Polyadenylate-polyuridylate
   * Polyadenylic.polyuridylic acid
   * Poly A . poly U
   * Poly (A) . poly (U) complex
   * Poly(rA) . poly(rU)
   * Poly(A.U)
   * Poly-rU:rA
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ANTBAL Antibiotiki.  (Moscow, USSR)  V.1-29, 1956-84.  For publisher
   information, see AMBIEH.  Volume(issue)/page/year: 21,642,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 375 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ANTBAL Antibiotiki.  (Moscow, USSR)  V.1-29, 1956-84.  For publisher
   information, see AMBIEH.  Volume(issue)/page/year: 21,642,1976
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human HeLa cell
DOSE/DURATION           : 5 mg/L
REFERENCE :
   PNASA6 Proceedings of the National Academy of Sciences of the United States
   of America.  (National Academy of Sciences, Printing & Pub. Office, 2101
   Constitution Ave., Washington, DC 20418) V.1-    1915-
   Volume(issue)/page/year: 70,3904,1973
 
                            *** END OF RECORD ***