*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : AU7482700 CHEMICAL NAME : 5'-Adenylic acid, polymers, complex with 5'-uridylic acid polymers (1:1) CAS REGISTRY NUMBER : 24936-38-7 LAST UPDATED : 199706 DATA ITEMS CITED : 3 MOLECULAR FORMULA : (C10-H14-N5-O7-P)n.(C9-H13-N2-O9-P)n COMPOUND DESCRIPTOR : Mutagen SYNONYMS/TRADE NAMES : * 5'-Adenylic acid, homopolymer, complex with 5'-uridylic acid homopolymer (1:1) * Polyadenylate-polyuridylate * Polyadenylic.polyuridylic acid * Poly A . poly U * Poly (A) . poly (U) complex * Poly(rA) . poly(rU) * Poly(A.U) * Poly-rU:rA *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ANTBAL Antibiotiki. (Moscow, USSR) V.1-29, 1956-84. For publisher information, see AMBIEH. Volume(issue)/page/year: 21,642,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 375 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ANTBAL Antibiotiki. (Moscow, USSR) V.1-29, 1956-84. For publisher information, see AMBIEH. Volume(issue)/page/year: 21,642,1976 ** MUTATION DATA ** TYPE OF TEST : DNA inhibition TEST SYSTEM : Human HeLa cell DOSE/DURATION : 5 mg/L REFERENCE : PNASA6 Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 1915- Volume(issue)/page/year: 70,3904,1973 *** END OF RECORD ***