*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AY4350000
CHEMICAL NAME           : Alanine, N-((2-chloroethyl)nitrosocarbamoyl)-
CAS REGISTRY NUMBER     : 80687-07-6
BEILSTEIN REFERENCE NO. : 5545020
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C6-H10-Cl-N3-O4
MOLECULAR WEIGHT        : 223.64
WISWESSER LINE NOTATION : QVY1&MVNNO&2G
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * N-((2-Chloroethyl)nitrosocarbamoyl)alanine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 45 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 19,512,1984
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA damage
TEST SYSTEM             : Rodent - rat Bone marrow
DOSE/DURATION           : 75 umol/kg
REFERENCE :
   55GNAX "Recent Advances in Chemotherapy, Proceedings of the International
   Congress of Chemotherapy, 14th, 1985," Tokyo, Univ. of Tokyo Press, 1985
   Volume(issue)/page/year: 1,483,1985
 
TYPE OF TEST            : DNA damage
TEST SYSTEM             : Rodent - rat Cells - not otherwise specified
DOSE/DURATION           : 75 umol/kg
REFERENCE :
   55GNAX "Recent Advances in Chemotherapy, Proceedings of the International
   Congress of Chemotherapy, 14th, 1985," Tokyo, Univ. of Tokyo Press, 1985
   Volume(issue)/page/year: 1,483,1985
 
                            *** END OF RECORD ***