*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AY5100000
CHEMICAL NAME           : beta-Alanine, N-(2,4-dihydroxy-3,3-dimethylbutyryl)-,
                          zinc salt (2:1), (R)-
CAS REGISTRY NUMBER     : 65979-81-9
LAST UPDATED            : 199209
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C18-H32-N2-O10.Zn
MOLECULAR WEIGHT        : 501.89
WISWESSER LINE NOTATION : Q1X1&1&YQVM2VO 2 &-ZN-
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   (T-4-(R),(R))-Bis(N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-beta-alanina
     to)zinc
   * (R)-N-(2,4-Dihydroxy-3,3-dimethylbutyryl)-beta-alanine zinc salt (2:1)
   * Pantothenate de zinc
   * Pantothenic acid, zinc salt
   * Zinc, bis(N-(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)-beta-alaninato)-,  
   (T-4-(R),(R))-
   * Zinc pantothenate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3763 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - ulceration or bleeding from stomach
REFERENCE :
   TOERD9 Toxicological European Research.  (S.P.E., 10, Ave. de Messine, 75008
   Paris, France) V.1-    1978-  Volume(issue)/page/year: 1,371,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 489 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - ulceration or bleeding from stomach
REFERENCE :
   TOERD9 Toxicological European Research.  (S.P.E., 10, Ave. de Messine, 75008
   Paris, France) V.1-    1978-  Volume(issue)/page/year: 1,371,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2161 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - ulceration or bleeding from stomach
REFERENCE :
   TOERD9 Toxicological European Research.  (S.P.E., 10, Ave. de Messine, 75008
   Paris, France) V.1-    1978-  Volume(issue)/page/year: 1,371,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 342 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - ulceration or bleeding from stomach
REFERENCE :
   TOERD9 Toxicological European Research.  (S.P.E., 10, Ave. de Messine, 75008
   Paris, France) V.1-    1978-  Volume(issue)/page/year: 1,371,1978
 
                            *** END OF RECORD ***