*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AY5960000
CHEMICAL NAME           : Alanine, 3-(3,4-dihydroxyphenyl)-, methyl ester, L-
CAS REGISTRY NUMBER     : 7101-51-1
BEILSTEIN REFERENCE NO. : 3056415
REFERENCE               : 4-14-00-02494 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C10-H13-N-O4
MOLECULAR WEIGHT        : 211.24
WISWESSER LINE NOTATION : QR BQ D1YZVO1
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * L-3-(3,4-Dihydroxyphenyl)alanine methyl ester
   * L-Dopa methyl ester
   * 3-Hydroxy-L-tyrosine methyl ester
   * Levodopa methyl ester
   * L-Tyrosine, 3-hydroxy-, methyl ester
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   CTRRDO Cancer Treatment Reports.  (Washington, DC)  V.60-71, 1976-87.  For
   publisher information,  see JNCIEQ.  Volume(issue)/page/year: 63,991,1979
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human Cells - not otherwise specified
DOSE/DURATION           : 3300 nmol/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   40,1414,1980
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - mouse Cells - not otherwise specified
DOSE/DURATION           : 3300 nmol/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   40,1414,1980
 
                            *** END OF RECORD ***