*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NM2620000
CHEMICAL NAME           : 1H-Indol-4-ol,
                          4-(2-(3,4-dimethoxyphenyl)ethenyl)octahydro-,
                          (3a-alpha,4-beta,4(Z),7a- alpha)-(+-)-,
                          (Z)-2-butenedioate (2:1) (salt)
CAS REGISTRY NUMBER     : 66690-81-1
LAST UPDATED            : 199510
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C36-H50-N2-O6.C4-H4-O4
MOLECULAR WEIGHT        : 722.96
SYNONYMS/TRADE NAMES :
   * Bis(3aRS,4SR,7aRS)-4-(3,4-dimethoxy-(Z)-styryl)hexahydro-4-idolinol  
   maleate
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 64 mg/kg/6D-C
TOXIC EFFECTS :
   Liver - other changes
   Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
   Biochemical - Metabolism (Intermediary) - lipids including transport
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   69,12,1983
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1400 mg/kg/8W-C
TOXIC EFFECTS :
   Liver - other changes
   Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
   Biochemical - Metabolism (Intermediary) - lipids including transport
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   69,12,1983
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 1680 mg/kg/12W-C
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - effect, not otherwise specified
   Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
   Biochemical - Metabolism (Intermediary) - lipids including transport
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   69,12,1983
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Primate - monkey
DOSE/DURATION           : 420 mg/kg/2W-C
TOXIC EFFECTS :
   Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
   Biochemical - Metabolism (Intermediary) - lipids including transport
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   69,12,1983
 
                            *** END OF RECORD ***