*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NM2625000
CHEMICAL NAME           : Indol-4-ol, 3-(2-(dimethylamino)ethyl)-
CAS REGISTRY NUMBER     : 520-53-6
BEILSTEIN REFERENCE NO. : 0160503
REFERENCE               : 5-22-12-00014 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C12-H16-N2-O
MOLECULAR WEIGHT        : 204.30
WISWESSER LINE NOTATION : T56 BMJ D2N1&1 FQ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * CX-59
   * 3-(2-(Dimethylamino)ethyl)indol-4-ol
   * 4-Hydroxy-N,N-dimethyltryptamine
   * Psilocin
   * Psilocine
   * Psilotsin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 75 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PSCBAY Psychopharmacology Service Center, Bulletin.  (Bethesda, MD)  V.1-3,
   1961-65.  For publisher information, see PSYBB9.  Volume(issue)/page/year:
   2,17,1963
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 196 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
REFERENCE :
   JTEHD6 Journal of Toxicology and Environmental Health.  (Hemisphere Pub.,
   1025 Vermont Ave., NW, Washington, DC 20005)  V.1-    1975/76-
   Volume(issue)/page/year: 1,515,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 74 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,138,1972
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 7 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and
   D.H. Efron, Washington, DC, 1972  Volume(issue)/page/year: -,138,1972

                              *** REVIEWS ***
 
   TOXICOLOGY REVIEW
   JMTHBU Journal of the Medical Association of Thailand.  (Businesss Mgr.,
   Dept. of Microbiology, Faculty of Medicine, Siriraj Hospital, Bangkok 7,
   Thailand)  V.1-    1918-  Volume(issue)/page/year: 58,623,1975

 
                            *** END OF RECORD ***