*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NM3289750
CHEMICAL NAME           : 2H-Indol-2-one,
                          1,3-dihydro-3-methoxy-1-(2-(4-morpholinyl)ethyl)-3-ph
                          enyl-, (Z)-2- butenedioate, hydrate (2:2:1)
CAS REGISTRY NUMBER     : 42773-66-0
LAST UPDATED            : 199109
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H24-N2-O3.C4-H4-O4.1/2H2-O
MOLECULAR WEIGHT        : 477.52
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1,3-Dihydro-3-methoxy-1-(2-(4-morpholinyl)ethyl)-3-phenyl-2H-indol-2-one  
   maleate hemihydrate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >200 mg/kg
TOXIC EFFECTS :
   Gastrointestinal - hypermotility, diarrhea
   Kidney, Ureter, Bladder - other changes
REFERENCE :
   CPBTAL Chemical and Pharmaceutical Bulletin.  (Japan Pub. Trading Co., USA,
   1255 Howard St., San Francisco, CA 94103)  V.6-    1958-
   Volume(issue)/page/year: 21,960,1973
 
                            *** END OF RECORD ***