*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NM3470000
CHEMICAL NAME           : 6H-Indolo(2,3-c)quinolin-6-one,
                          5,7-dihydro-10-chloro-5-(2-(dimethylamino)ethyl)-,
                          monohydrochloride
CAS REGISTRY NUMBER     : 63190-28-3
LAST UPDATED            : 198308
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C19-H18-Cl-N3-O.Cl-H
MOLECULAR WEIGHT        : 376.31
WISWESSER LINE NOTATION : T C6 B656 INV LMJ I2N1&1 PG &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 10-Chloro-5-(2-dimethylaminoethyl)-6H-indolo(2,3-c)quinolin-6(5H)-one  
   hydrochloride
   * CIQ
   *   5,7-Dihydro-10-chloro-5-(2-(dimethylamino)ethyl)-6H-indolo(2,3-c)quinoli
     n-6-one HCl
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 960 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   CHTHBK Chemotherapy (Basel).  (S. Karger Pub., Inc., 79 Fifth Ave., New
   York, NY 10003) V.13-    1968-  Volume(issue)/page/year: 24,77,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 690 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   CHTHBK Chemotherapy (Basel).  (S. Karger Pub., Inc., 79 Fifth Ave., New
   York, NY 10003) V.13-    1968-  Volume(issue)/page/year: 24,77,1978
 
                            *** END OF RECORD ***