*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NM3472000
CHEMICAL NAME           : 1H-Indolo(2,3-c)quinolin-1-one,
                          2,3,4,7-tetrahydro-3,3-dimethyl-6-(trifluoromethyl)-,
                          monohydrochloride
CAS REGISTRY NUMBER     : 96725-30-3
LAST UPDATED            : 198703
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C18-H15-F3-N2-O.Cl-H
MOLECULAR WEIGHT        : 368.81
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   3,3-Dimethyl-6-trifluoromethyl-1-oxo-1,2,3,4-tetrahydroindolo(2,3-c)quin
     oline hydrochloride
   *   2,3,4,7-Tetrahydro-3,3-dimethyl-6-(trifluoromethyl)-1H-indolo(2,3-c)quin
     olin-1-one HCl
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 19,187,1985
 
                            *** END OF RECORD ***