*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : NM2083780 CHEMICAL NAME : 2-Indolinone, 3,3-bis(p-hydroxyphenyl)- CAS REGISTRY NUMBER : 125-13-3 BEILSTEIN REFERENCE NO. : 0286070 REFERENCE : 5-21-13-00398 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C20-H15-N-O3 MOLECULAR WEIGHT : 317.36 COMPOUND DESCRIPTOR : Drug Human SYNONYMS/TRADE NAMES : * 3,3-Bis(p-hydroxyphenyl)-2-indolinone * 1,3-Dihydro-3,3-bis(4-hydroxyphenyl)-2H-indol-2-one * 4,4'-Dihydroxydiphenylisatin * Diphenolisatin * Hoscolax * 2H-Indol-2-one, 1,3-dihydro-3,3-bis(4-hydroxyphenyl)- * Isatinbisphenol * Isolax * Lavema * Neodrast * Normalax * Oxyphenisatin * Oxyphenisatine * Phenolisatin * Propellax * Recolon * Veripaque *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - woman DOSE/DURATION : 300 ug/kg/36H-I TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Liver - jaundice, other or unclassified Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases REFERENCE : NEJMAG New England Journal of Medicine. (Massachusetts Medical Soc., 10 Shattuck St., Boston, MA 02115) V.198- 1928- Volume(issue)/page/year: 285,813,1971 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - man DOSE/DURATION : 214 ug/kg/1D TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Liver - jaundice, other or unclassified Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases REFERENCE : NEJMAG New England Journal of Medicine. (Massachusetts Medical Soc., 10 Shattuck St., Boston, MA 02115) V.198- 1928- Volume(issue)/page/year: 285,813,1971 *** END OF RECORD ***