*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NO2160300
CHEMICAL NAME           : Ipomoea muricata (L.) Jacq., seed extract
SUBSTANCE DEFINITION :
   Plant belonging to the family Convolvulaceae
REFERENCE :
   AMNIB6 Acta Manilana, Series A: Natural and Applied Sciences.  (Univ. of
   Santo Tomas Research Center, Manila, D-403, Philippines)  V.4-    1968-
LAST UPDATED            : 199506
DATA ITEMS CITED        : 2
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Calonyction muricatum Linn., seed extract
   * Dominican bean
   * Tonkin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 7810 mg/kg
TOXIC EFFECTS :
   Behavioral - analgesia
   Lungs, Thorax, or Respiration - respiratory depression
   Gastrointestinal - hypermotility, diarrhea
REFERENCE :
   AMNIB6 Acta Manilana, Series A: Natural and Applied Sciences.  (Univ. of
   Santo Tomas Research Center, Manila, D-403, Philippines)  V.4-    1968-
   Volume(issue)/page/year: 19,3,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 490 mg/kg
TOXIC EFFECTS :
   Behavioral - analgesia
   Gastrointestinal - nausea or vomiting
   Blood - changes in cell count (unspecified)
REFERENCE :
   AMNIB6 Acta Manilana, Series A: Natural and Applied Sciences.  (Univ. of
   Santo Tomas Research Center, Manila, D-403, Philippines)  V.4-    1968-
   Volume(issue)/page/year: 17,20,1978
 
                            *** END OF RECORD ***