*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NM2208600
CHEMICAL NAME           : 2-Indolinone,
                          3-(4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5
                          -yl)-1-methyl-, hydrochloride
LAST UPDATED            : 198603
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H22-N2-O4.Cl-H
MOLECULAR WEIGHT        : 402.91
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Anhydrocotarnine-N-methyloxindol chloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 260 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - muscle weakness
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   QJPPAL Quarterly Journal of Pharmacy & Pharmacology.  (London, UK)  V.2-21,
   1929-48.  For publisher information, see JPPMAB.  Volume(issue)/page/year:
   10,67,1937
 
                            *** END OF RECORD ***