*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NO5425000
CHEMICAL NAME           : Iron(3+) chloride, hexahydrate
CAS REGISTRY NUMBER     : 10025-77-1
LAST UPDATED            : 199703
DATA ITEMS CITED        : 14
MOLECULAR FORMULA       : Cl3-Fe.6H2-O
MOLECULAR WEIGHT        : 270.32
WISWESSER LINE NOTATION :  FE  G3 &QH 6
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * Ferric chloride, hexahydrate
   * Ferric trichloride hexahydrate
   * Iron (III), chloride, hexahydrate
   * Iron trichloride hexahydrate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 900 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EQSSDX Environmental Quality and Safety, Supplement.  (Stuttgart, Fed. Rep.
   Ger.)  V.1-5, 1975-76. Discontinued.  Volume(issue)/page/year: 1,1,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 260 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JAFCAU Journal of Agricultural and Food Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC
   20037)  V.1-    1953-  Volume(issue)/page/year: 14,512,1966
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 7200 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EQSSDX Environmental Quality and Safety, Supplement.  (Stuttgart, Fed. Rep.
   Ger.)  V.1-5, 1975-76. Discontinued.  Volume(issue)/page/year: 1,1,1975
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 61250 mg/kg/14W-C
TOXIC EFFECTS :
   Liver - changes in liver weight
   Kidney, Ureter, Bladder - changes in bladder weight
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - dehydrogenases
REFERENCE :
   ESKHA5 Eisei Shikenjo Hokoku.  Bulletin of the Institute of Hygienic
   Sciences.  (Kokuritsu Eisei Shikenjo Kagaku, 18-1 Bushitsu Johobu,
   Setagaya-ku, Tokyo 158, Japan)  V.1-    1886-  Volume(issue)/page/year:
   103,21,1985
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Multiple routes
TEST SYSTEM             : Non-mammalian species
DOSE/DURATION           : 4500 ug/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 370,19,1996
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 4800 umol/L
REFERENCE :
   IAAAAM International Archives of Allergy and Applied Immunology.  (S. Karger
   Pub., Inc., 79 Fifth Ave., New York, NY 10003)  V.1-    1950-
   Volume(issue)/page/year: 79,83,1986
 
TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Rodent - rat Ascites tumor
DOSE/DURATION           : 500 mg/kg
REFERENCE :
   GANNA2 Gann.  Japanese Journal of Cancer Research.  (Tokyo, Japan)  V.1-75,
   1907-84.  For publisher information, see JJCREP.  Volume(issue)/page/year:
   54,155,1963

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   MSHA STANDARD-air:TWA 1 mg(Fe)/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   3,138,1971

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-DENMARK:TWA 1 mg(Fe)/m3 JAN 1993
   
   OEL-FINLAND:TWA 1 mg(Fe)/m3 JAN 1993
   
   OEL-THE NETHERLANDS:TWA 1 mg(Fe)/m3 JAN 1993
   
   OEL-SWITZERLAND:TWA 1 mg(Fe)/m3 JAN 1993
   
   OEL-UNITED KINGDOM:TWA 1 mg(Fe)/m3;STEL 2 mg(Fe)/m3 JAN 1993

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X4675
       No. of Facilities: 100 (estimated)
       No. of Industries: 4
       No. of Occupations: 4
       No. of Employees: 871 (estimated)
       No. of Female Employees: 465 (estimated)

 
                            *** END OF RECORD ***