*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NO7400000
CHEMICAL NAME           : Iron(III) oxide
CAS REGISTRY NUMBER     : 1309-37-1
OTHER CAS REGISTRY NOS. : 8011-97-0
LAST UPDATED            : 199712
DATA ITEMS CITED        : 44
MOLECULAR FORMULA       : Fe2-O3
MOLECULAR WEIGHT        : 159.70
WISWESSER LINE NOTATION :  FE2 O3
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * Anchred standard
   * Anhydrous iron oxide
   * Anhydrous oxide of iron
   * Armenian bole
   * Bauxite residue
   * Black oxide of iron
   * Blended red oxides of iron
   * Burntisland Red
   * Burnt umber
   * Calcotone Red
   * Caput mortuum
   * Colcothar
   * Colloidal ferric oxide
   * C.I. 77491
   * C.I. Pigment Red 101
   * C.I. Pigment Red 102
   * C.I. Pigment Red 101 and 102
   * Crocus martis adstringens
   * Deanox
   * Deanox DNX Pigments
   * Eisenoxyd
   * English Red
   * Ferric oxide
   * Ferric oxide (colloidal)
   * Ferrugo
   * Iron oxide
   * Iron Oxide Red
   * Iron oxide pigments
   * Iron Red
   * Iron sesquioxide
   * Jeweler's rouge
   * Levanox Red 130A
   * Light Red
   * Manufactured iron oxides
   * Mars Brown
   * Mars Red
   * Natural iron oxides
   * Natural Red Oxide
   * Ochre
   * Prussian Brown
   * Quick rouge
   * Raddle
   * 11554 Red
   * Red Iron Oxide
   * Red ochre
   * Red oxide
   * Red oxide D3452
   * Red oxide D6984
   * Red oxide of iron
   * Rouge
   * Rubigo
   * Sienna
   * Specular iron
   * Stone Red
   * Supra
   * Synthetic iron oxide
   * Venetian Red
   * Vitriol Red
   * Vogel's Iron Red
   * Yellow ferric oxide
   * Yellow oxide of iron
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 30 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HBAMAK "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig,
   Ger. Dem. Rep.)  Volume(issue)/page/year: 4,1289,1935
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 500 ug/m3/24H/61D-C
TOXIC EFFECTS :
   Brain and Coverings - other degenerative changes
   Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - true cholinesterase
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 50(7),73,1985
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 135 mg/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   PBPHAW Progress in Biochemical Pharmacology.  (S. Karger AG, Postfach
   CH-4009 Basel, Switzerland) V.1-    1965-  Volume(issue)/page/year:
   14,47,1978

                              *** REVIEWS ***
 
   ACGIH TLV-Not classifiable as a human carcinogen
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   ACGIH TLV-TWA 10 mg/m3, Inhalable dust
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   IARC Cancer Review:Animal NO EVIDENCE
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 1,29,1972

   IARC Cancer Review:Human Inadequate Evidence
   IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
   to Man.  (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
   V.1-    1972-  Volume(issue)/page/year: 1,29,1972

   IARC Cancer Review:Group 3
   IMSUDL IARC Monographs, Supplement.  (WHO Publications Centre USA, 49
   Sheridan Ave., Albany, NY 12210)  No.1-    1979-  Volume(issue)/page/year:
   7,216,1987

   TOXICOLOGY REVIEW
   ZKKOBW Zeitschrift fuer Krebsforschung und Klinische Onkologie.  (Berlin,
   Fed. Rep. Ger.)  V.76-92, 1971-78.  For publisher information, see JCROD7.
   Volume(issue)/page/year: 78,99,1972

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   MSHA STANDARD:NUISANCE PARTICULATES
   DTLWS* "Documentation of the Threshold Limit Values for Substances in
   Workroom Air," Supplements. For publisher information, see 85INA8.
   Volume(issue)/page/year: 3,27,1973

   OSHA PEL (Gen Indu):8H TWA 15 mg/m3, total dust
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1910.1000,1994

   OSHA PEL (Gen Indu):8H TWA 5 mg/m3, respirable fraction
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1910.1000,1994

   OSHA PEL (Construc):8H TWA 15 mg/m3, total dust
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1926.55,1994

   OSHA PEL (Construc):8H TWA 5 mg/m3, respirable fraction
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1926.55,1994

   OSHA PEL (Shipyard):8H TWA 15 mg/m3, total dust
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1915.1000,1993

   OSHA PEL (Shipyard):8H TWA 5 mg/m3, respirable fraction
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1915.1000,1993

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-ARAB Republic of Egypt:TWA 3 ppm (5 mg/m3) (fume) JAN 1993
   
   OEL-AUSTRALIA:TWA 5 mg/m3 (fume) JAN 1993
   
   OEL-BELGIUM:TWA 2 ppm (5 mg/m3) (fume) JAN 1993
   
   OEL-DENMARK:TWA 3.5 mg/m3 (fume) JAN 1993
   
   OEL-FINLAND:TWA 5 ppm (fume) JAN 1993
   
   OEL-FRANCE:TWA 5 mg/m3 (fume) JAN 1993
   
   OEL-GERMANY:TWA 6 mg/m3 (fume) JAN 1993
   
   OEL-THE NETHERLANDS:TWA 10 mg/m3 JAN 1993
   
   OEL-THE NETHERLANDS:TWA 5 mg/m3 (fume) JAN 1993
   
   OEL-THE PHILIPPINES:TWA 10 mg/m3 (fume) JAN 1993
   
   OEL-POLAND:TWA 5 mg/m3 (fume) JAN 1993
   
   OEL-SWEDEN:TWA 3.5 mg/m3 (fume) JAN 1993
   
   OEL-SWITZERLAND:TWA 2 ppm (5 mg/m3) (fume) JAN 1993
   
   OEL-THAILAND:TWA 10 mg/m3 (fume) JAN 1993
   
   OEL-TURKEY:TWA 10 mg/m3 (fume) JAN 1993
   
   OEL-UNITED KINGDOM:TWA 10 mg/m3 (total dust) JAN 1993
   
   OEL-UNITED KINGDOM:TWA 5 mg/m3 (resp. dust) JAN 1993
   
   OEL-UNITED KINGDOM:TWA 5 mg/m3;STEL 10 mg/m3 (fume) JAN 1993
   
   OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
   
   OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
   NIOSH REL TO IRON OXIDE, dust and fume (as Fe)-air:10H TWA 5 mg/m3
REFERENCE :
   NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
   Health, Education, and Welfare, Reports and Memoranda.
   Volume(issue)/page/year: DHHS #92-100,1992

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - M1463
       No. of Facilities: 41132 (estimated)
       No. of Industries: 265
       No. of Occupations: 153
       No. of Employees: 483117 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - M1463
       No. of Facilities: 62557 (estimated)
       No. of Industries: 308
       No. of Occupations: 185
       No. of Employees: 965275 (estimated)
       No. of Female Employees: 139397 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
   
   NIOSH Analytical Method, 1994: Elements by ICP, 7300
   
   OSHA ANALYTICAL METHOD #ID-125G

 
                            *** END OF RECORD ***