*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NR0147000
CHEMICAL NAME           : Isocyanic acid, m-phenylenedimethylene ester
CAS REGISTRY NUMBER     : 3634-83-1
BEILSTEIN REFERENCE NO. : 0781825
REFERENCE               : 4-13-00-00293 (Beilstein Handbook Reference)
LAST UPDATED            : 199701
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C10-H8-N2-O2
MOLECULAR WEIGHT        : 188.20
COMPOUND DESCRIPTOR     : Primary Irritant
SYNONYMS/TRADE NAMES :
   * Benzene, 1,3-bis(isocyanatomethyl)-
   * 1,3-Bis(isocyanatomethyl)benzene
   * 1,3-Bis-(isokyanatomethyl)benzen
   * m-Phenylenedimethylene isocyanate
   * Takenate
   * Takenate 500
   * M-Xdi
   * m-Xylene diisocyanate
   * m-Xylidene diisocyanate
   * m-Xylylendiisokyanat
   * m-Xylylene diisocyanate
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 2 mg/24H
REACTION SEVERITY       : Severe
REFERENCE :
   85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
   Prague, Czechoslovakia, Avicenum, 1986  Volume(issue)/page/year: -,933,1986
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 5 mg/24H
REACTION SEVERITY       : Severe
REFERENCE :
   85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
   Prague, Czechoslovakia, Avicenum, 1986  Volume(issue)/page/year: -,933,1986
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5350 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
   Prague, Czechoslovakia, Avicenum, 1986  Volume(issue)/page/year: -,933,1986
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 840 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TAKHAA Takeda Kenkyusho Ho.  Journal of the Takeda Research Laboratories.
   (Takeda Yakuhin Kogyo K.K., 2-17-85 Jusohon-machi, Yodogawa-ku, Osaka 532,
   Japan)  V.29-    1970-  Volume(issue)/page/year: 39,202,1980

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***