*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NR3885000
CHEMICAL NAME           : 1H-Isoindol-1-one,
                          2-(2-(diethylamino)ethyl)-2,3-dihydro-3-phenyl-,
                          phosphate
CAS REGISTRY NUMBER     : 26070-68-8
LAST UPDATED            : 199204
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C20-H24-N2-O.xH3-O4-P
MOLECULAR WEIGHT        : 994.46
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-(2-(Diethylamino)ethyl)-2,3-dihydro-3-phenyl-1H-isoindol-1-one  
   phosphate
   * 2-(beta-Diethylaminoethyl)-3-phenylphthalimidine phosphate
   * Gitan
   * Phthalimidine, 2-(2-(diethylamino)ethyl)-3-phenyl-, phosphate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 287 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 185,47,1970
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 103 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 185,47,1970
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 58 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Behavioral - convulsions or effect on seizure threshold
   Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 185,47,1970
 
                            *** END OF RECORD ***