*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : NR3885000 CHEMICAL NAME : 1H-Isoindol-1-one, 2-(2-(diethylamino)ethyl)-2,3-dihydro-3-phenyl-, phosphate CAS REGISTRY NUMBER : 26070-68-8 LAST UPDATED : 199204 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C20-H24-N2-O.xH3-O4-P MOLECULAR WEIGHT : 994.46 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * 2-(2-(Diethylamino)ethyl)-2,3-dihydro-3-phenyl-1H-isoindol-1-one phosphate * 2-(beta-Diethylaminoethyl)-3-phenylphthalimidine phosphate * Gitan * Phthalimidine, 2-(2-(diethylamino)ethyl)-3-phenyl-, phosphate *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 287 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 185,47,1970 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 103 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 185,47,1970 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Mammal - cat DOSE/DURATION : 58 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - convulsions or effect on seizure threshold Gastrointestinal - changes in structure or function of salivary glands REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 185,47,1970 *** END OF RECORD ***