*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NS1360000
CHEMICAL NAME           : Isonicotinic acid, 2,6-dichloro-, hydrazide
CAS REGISTRY NUMBER     : 57803-51-7
BEILSTEIN REFERENCE NO. : 0152207
REFERENCE               : 1-22-00-00505 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C6-H5-Cl2-N3-O
MOLECULAR WEIGHT        : 206.04
WISWESSER LINE NOTATION : T6NJ BG DVMZ FG
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2,6-Dichloroisonicotinic acid hydrazide
   * 2,6-Dichlor-isonicotinsaeurehydrazid
   * Hydrazide of 2,6-dichloroisonicotinic acid
   * 4-Pyridinecarboxylic acid, 2,6-dichloro-, hydrazide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 340 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   HCACAV Helvetica Chimica Acta.  (Verlag Helvetica Chimica Acta, Postfach,
   CH-4002 Basel, Switzerland) V.1-    1918-  Volume(issue)/page/year:
   38,1033,1955
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 10,252,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 180 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Aberdeen Proving Ground, MD 21010)
   Volume(issue)/page/year: NX#05034
 
                            *** END OF RECORD ***