*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NS1752600
CHEMICAL NAME           : Isonicotinic acid hydrazide, hydrazone with
                          D-mannuronic acid lactone
LAST UPDATED            : 198408
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C12-H13-N3-O6
MOLECULAR WEIGHT        : 295.28
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * D-Mannuronolactone isonicotinyl hydrazone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1100 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 44,591,1955
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1400 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 44,591,1955
 
                            *** END OF RECORD ***