*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NS1790010
CHEMICAL NAME           : Isonicotinic acid, (o-hydroxybenzylidene)hydrazide
CAS REGISTRY NUMBER     : 495-84-1
LAST UPDATED            : 199706
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C13-H11-N3-O2
MOLECULAR WEIGHT        : 241.27
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Isonicotinic acid, 2-hydroxybenzylidenehydrazide
   * Isonicotinic acid, salicylidenehydrazide
   * 4-Pyridinecarboxylic acid, ((2-hydroxyphenyl)methylene)hydrazide
   * Salinazid
   * Salinazida
   * Salinazide
   * Salinazidum
   * Saliniazid
   * Saliniazidum
   * Salizid
   * Salizide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 53,1036,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >20 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ABANAE Antibiotics Annual.  (New York, NY)  1953-60.  For publisher
   information, see AMACCQ.  Volume(issue)/page/year: 2,442,1954/1955
 
                            *** END OF RECORD ***