*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NS4910000
CHEMICAL NAME           : Isonipecotamide,
                          1-(3-(2-chlorophenothiazin-10-yl)propyl)-4-piperidino
                          -, hydrochloride, methanol (1:2:1)
CAS REGISTRY NUMBER     : 13805-43-1
LAST UPDATED            : 198609
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C26-H33-Cl-N4-O-S.2Cl-H.C-H4-O
MOLECULAR WEIGHT        : 589.10
WISWESSER LINE NOTATION : T C666 BN ISJ EG B3- AT6NTJ DVZ D- AT6NTJ &Q1 &GH 2
COMPOUND DESCRIPTOR     : Drug
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 80 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - changes in motor activity (specific assay)
   Behavioral - antianxiety
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 13,644,1970
 
                            *** END OF RECORD ***