*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : NS5265500 CHEMICAL NAME : Isonipecotic acid, 1-(2-(benzyloxy)ethyl)-4-phenyl-, ethyl ester CAS REGISTRY NUMBER : 3691-78-9 BEILSTEIN REFERENCE NO. : 0334584 REFERENCE : 5-22-02-00472 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C23-H29-N-O3 MOLECULAR WEIGHT : 367.53 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * Benzethidin * Benzethidine * Ethyl 1-(2-benzyloxyethyl)-4-phenylpiperidine-4-carboxylate * NIH 7574 * 4-Piperidinecarboxylic acid, 4-phenyl-1-(2-(phenylmethoxy)ethyl)-, ethyl ester *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 284 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) REFERENCE : BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 15,254,1960 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 600 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) REFERENCE : BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 15,254,1960 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 10900 ug/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) REFERENCE : BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 15,254,1960 *** END OF RECORD ***