*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : NS5360000 CHEMICAL NAME : Isonipecotic acid, 1-(4,4-diphenyl-3-butenyl)-4-phenyl-, ethyl ester, hydrochloride CAS REGISTRY NUMBER : 14106-90-2 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C30-H33-N-O2.Cl-H MOLECULAR WEIGHT : 476.10 WISWESSER LINE NOTATION : T6NTJ A3UYR&R& DVO2 DR &GH COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * 1-(4,4-Diphenyl-3-butenyl)-4-phenylisonipecotic acid ethyl ester hydrochloride * 4-Piperidinecarboxylic acid, 1-(4,4-diphenyl-3-butenyl)-4-phenyl-, ethyl ester hydrochloride *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1200 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 10,627,1967 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 380 mg/kg TOXIC EFFECTS : Behavioral - analgesia REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 10,627,1967 *** END OF RECORD ***