*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NS5415000
CHEMICAL NAME           : Isonipecotic acid,
                          1-(beta-hydroxyphenethyl)-4-phenyl-, ethyl ester,
                          hydrochloride
CAS REGISTRY NUMBER     : 95132-59-5
LAST UPDATED            : 199412
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C22-H27-N-O3.Cl-H
MOLECULAR WEIGHT        : 389.96
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-(beta-Hydroxyphenethyl)-4-phenylisonipecotic acid ethyl ester  
   hydrochloride
   * Oxfeneridin
   * Oxfeneridine
   * 2-Phenyl-2-hydroxyethylnorpethidine hydrochloride
   * VUFB2752
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 116 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JOCEAH Journal of Organic Chemistry.  (American Chemical Soc., Distribution
   Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037)  V.1-
   1936-  Volume(issue)/page/year: 21,125,1956
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 18500 ug/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   CKFRAY Ceskoslovenska Farmacie.  (PNS-Ustredni Expedice a Dovoz Tisku,
   Kafkova 19, 160 00 Prague 6, Czechoslovakia)  V.1-    1952-
   Volume(issue)/page/year: 12,450,1963
 
                            *** END OF RECORD ***